Francesco Costabile studied film at the University of Bologna, where he made his first short film, La sua gamba (2001), which won kudos at the Bellaria Film Festival in 2002. Next, he studied directing at the Centro Sperimentale di Cinematografia in Rome, making the shorts L’armadio and Dentro Roma, the latter of which won a Silver Ribbon for Best Short and was nominated for a David di Donatello in the same category. He wrote various screenplays with a queer theme, then turned to documentaries, making two about the costume designer Piero Tosi (L’abito e il volto, 2009, Audience Award at the 2010 Biografilm Festival, and Piero Tosi 1690, in 2014). Costable continued to explore the biopic genre in the documentary In un futuro Aprile, about Pier Paolo Pasolini and his ties to his native Friuli and its dialect. This film was shortlisted for the 2021 Silver Ribbons and won numerous awards. In 2017, he produced the film Porno e Libertà by Carmine Amoroso with Zut Film. The same year, Costabile founded the queer and post-porn Hacker Porn Film Festival with filmmaker Lucio Massa.